Name: Pepperoni Pizza Chicken Bake
Prep time: 15 min
Cook time: 35 min
Total time: 50 min
Ingredients: 1 jar Low-Sugar Pizza Sauce (reduced to 1 cup); 4 pieces Boneless-Skinless Chicken Breasts (very large, each at least 8 oz); 1 tablespoon Olive Oil; 1 teaspoon Greek Oregano; 1 teaspoon Garlic Powder (or fresh garlic); 6 oz Mozzarella Cheese (sliced about 1/4 inch thick); 2 oz Pepperoni (sliced (regular or turkey))

Jump to Recipe Print Recipe

If you’re a fan of pizza and chicken, then this Pepperoni Pizza Chicken Bake is about to become your new favorite weeknight meal. Imagine juicy, tender chicken breasts topped with a rich, flavorful pizza sauce, melted mozzarella cheese, and the irresistible crunch of pepperoni. This dish packs all the classic pizza flavors into a healthy, satisfying dinner that the whole family will love. Plus, it’s super easy to throw together, making it perfect for busy evenings or when you want to impress your guests without spending hours in the kitchen. Let’s dive into the delicious details!

Top Reasons to Make Pepperoni Pizza Chicken Bake

Simple Preparation: This recipe requires minimal prep work, making it a great option for busy weeknights.
Flavor-Packed: Each bite is bursting with the classic flavors of pepperoni pizza, sure to satisfy your cravings.
Healthy Twist: Swap out traditional pizza crust for lean chicken breasts for a healthier alternative.
Customizable: You can easily modify the toppings to suit your taste preferences.
Family-Friendly: Kids and adults alike will love this fun and flavorful dish.

Ingredient Notes

Low-Sugar Pizza Sauce: Use 1 jar (14 oz) of low-sugar pizza sauce, reduced to 1 cup. This keeps the dish flavorful without excess sugar. Look for brands that prioritize natural ingredients.
Boneless-Skinless Chicken Breasts: You’ll need 4 very large chicken breasts, each weighing at least 8 oz. This ensures they stay juicy and tender throughout the baking process.
Olive Oil: Just a tablespoon of olive oil adds richness and helps with browning.
Greek Oregano: A teaspoon of this herb enhances the pizza flavor profile beautifully.
Garlic Powder: This adds a savory depth to the dish. If you prefer fresh garlic, feel free to substitute.
Mozzarella Cheese: Use 6 oz of fresh mozzarella sliced about 1/4 inch thick for that gooey, melty goodness.
Pepperoni: 2 oz of sliced pepperoni (regular or turkey) provides the classic pizza topping. Choose your favorite variety!

Hardware & Gadgets

9×13-inch Baking Dish: Perfect for holding all your ingredients and ensuring even cooking.
Sharp Knife: For slicing the mozzarella and prepping your chicken.
Meat Thermometer: Optional, but useful for ensuring your chicken is cooked to the perfect internal temperature.
Stirring Spoon: To mix your sauce and toppings together effortlessly.

Cooking Pepperoni Pizza Chicken Bake: The Process

Step 1: Preheat the Oven

Preheat your oven to 375°F (190°C). This ensures that your chicken bakes evenly and becomes tender.

Step 2: Prepare the Chicken

In a large baking dish, drizzle the olive oil over the bottom. Place the boneless-skinless chicken breasts in the dish, ensuring they are evenly spaced.

Step 3: Season the Chicken

Sprinkle the Greek oregano and garlic powder evenly over the chicken breasts. This will infuse them with flavor as they bake.

Step 4: Add the Pizza Sauce

Pour the reduced pizza sauce evenly over the chicken breasts, making sure they are well covered. This sauce will keep the chicken moist and flavorful.

Step 5: Layer the Cheese

Arrange the slices of mozzarella cheese over the chicken and sauce. Don’t be shy; you want a nice, cheesy layer!

Step 6: Top with Pepperoni

Finally, add the sliced pepperoni on top of the cheese. Feel free to layer them on generously for that classic pizza vibe.

Step 7: Bake

Place the baking dish in your preheated oven and bake for about 30-35 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F (74°C). The cheese should be bubbly and slightly golden.

Step 8: Serve

Once baked, remove the dish from the oven and let it cool for a few minutes. Serve hot, and enjoy your Pepperoni Pizza Chicken Bake with a side salad or your favorite veggies.

Make It Your Way

Vegetable Add-Ins: Consider adding sliced bell peppers, mushrooms, or olives for extra flavor and nutrition.
Cheese Variations: Try using provolone, cheddar, or even a vegan cheese alternative if you prefer.
Spice It Up: Add red pepper flakes or Italian seasoning for a little extra kick.
Swap the Meat: Use turkey breasts or even tofu for a vegetarian option.

Don’t Do This

Don’t Overbake: Keep an eye on your chicken; overbaking can lead to dry, tough meat.
Don’t Skip the Sauce: The sauce is crucial for keeping the chicken moist and adding flavor—don’t leave it out!
Don’t Use Low-Quality Cheese: Fresh mozzarella makes a big difference in taste and texture.
Don’t Forget to Rest: Allow the dish to cool briefly before serving to let the flavors meld.

Shelf Life & Storage

This Pepperoni Pizza Chicken Bake can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, simply place it in the oven or microwave until warmed through. For longer storage, consider freezing the dish. It should last for up to 3 months in the freezer. To reheat, thaw overnight in the refrigerator, then bake until heated through.

Your Questions, Answered

Can I use frozen chicken breasts for this recipe?

It’s best to use thawed chicken breasts for even cooking. If you have frozen chicken, thaw them in the refrigerator before using them in this recipe.

What can I serve with Pepperoni Pizza Chicken Bake?

This dish pairs well with a simple side salad, steamed vegetables, or garlic bread for a complete meal.

Can I make this dish ahead of time?

Yes! You can prepare the dish ahead of time and store it in the refrigerator. Just bake it right before serving for the best results.

Is this dish suitable for meal prep?

Absolutely! This recipe is perfect for meal prepping. Portion it out into individual containers for easy grab-and-go lunches or dinners throughout the week.

Don’t Miss These

Sally’s Baking Addiction – For more delicious baking ideas.
Pinch of Yum – Explore more mouthwatering recipes.
Minimalist Baker – Find simple and amazing recipes.
Food Network – Discover a variety of cooking shows and recipes.

Time to Try It

Now that you have the full rundown on how to make this irresistible Pepperoni Pizza Chicken Bake, it’s time to roll up your sleeves and get cooking! This dish brings together the best of both worlds—pizza and chicken—creating a meal that’s sure to please everyone at your table. Enjoy the process and the delicious flavors that come together in this easy-to-make recipe. Happy baking!