In a large mixing bowl, combine the drained canned salmon, large egg, mayonnaise, Dijon mustard, lemon juice, finely chopped onion, panko breadcrumbs, chopped parsley, seafood seasoning, salt, and pepper. Use a fork to mix everything until well combined.
Once your mixture is ready, use your hands to form it into patties, about 1/2 inch thick.
Preheat your air fryer to 375°F (190°C) for about 5 minutes.
Spray the air fryer basket with cooking spray and place the salmon patties in a single layer, ensuring not to overcrowd them.
Cook the patties for 10-12 minutes, flipping halfway through, until golden brown and crispy.
Carefully remove the patties from the air fryer and serve hot with your favorite dipping sauce.