Preheat the broiler and move the top oven rack to be about 6 to 8 inches from the heating element. Line a sheet pan with aluminum foil.

Rinse the 4 tilapia fillets and pat them dry with paper towels.

Season both sides of the fillets with 1/2 teaspoon kosher salt, 1/4 teaspoon fresh black pepper, and 1 tablespoon finely chopped fresh oregano, or 1 teaspoon dried.

Arrange the seasoned fillets in a single layer on the prepared sheet pan.

Evenly sprinkle the 2 garlic cloves, minced, over the fillets.

Drizzle the 4 teaspoons olive oil evenly over the fillets.

Evenly sprinkle the 2 tablespoons whole wheat seasoned breadcrumbs, or gluten-free crumbs, over the fillets.

Set the broiler to low and place the sheet pan on the rack. Broil for about 6 to 8 minutes, watching closely, until the breadcrumbs are golden brown and the fish is cooked through and flakes easily with a fork. Be careful not to burn.

Remove from the oven and serve immediately with lemon wedges.