Preheat the oven to 400°F (207°C).
Pat the salmon dry with paper towels and season both sides with salt and ground black pepper.
In a small bowl, melt the butter (microwave 10–15 seconds or warm gently on the stove), then stir in honey, minced garlic, 1/4 teaspoon salt, cayenne (if using), and chopped parsley to make the honey garlic butter.
Place two large sheets of aluminum foil on a baking sheet and set the salmon on top. Spoon half of the honey garlic butter over the salmon and spread evenly.
Wrap the foil tightly around the salmon to seal and prevent leaks.
Bake in the preheated oven for 15 minutes.
Carefully unwrap the foil, spoon out any excess liquid that collected, then drizzle the remaining honey garlic butter over the salmon and squeeze lemon wedges over top before serving.